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Foldit

Puzzle video gameprotein folding

Foldit is an online puzzle video game about protein folding. It is part of an experimental research project developed by the University of Washington, Center for Game Science, in collaboration with the UW Department of Biochemistry. The objective of Foldit is to fold the structures of selected proteins as perfectly as possible, using tools provided in the game. The highest scoring solutions are analyzed by researchers, who determine whether or not there is a native structural configuration (native state) that can be applied to relevant proteins in the real world. Scientists can then use these solutions to target and eradicate diseases and create biological innovations.
A 2010 paper in the science journal Nature credited Foldit's 57,000 players with providing useful results that matched or outperformed algorithmically computed solutions.
Developed by University of Washington, Center for Game Science, Department of Biochemistry

Foldit Alternatives

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  • FlyExpress

    FlyExpress is a free database that collects the expression patterns of Drosophila melanogaster in embryogenesis via a series of images submitted from BDGP, Fly-FISH and publications from other...

    Tags: Insect Developmental Biology, Model Organism Databases, Bioinformatics Software
  • FASTA by Pearson W.R.

    FASTA is a DNA and protein sequence alignment software package first described (as FASTP) by David J. Lipman and William R. Pearson in 1985. Its legacy is the FASTA format which is now ubiquitous in...

    Tags: Computational Phylogenetics, Bioinformatics Software
  • esyN

    esyN (Easy Networks) is an open source bioinformatics web-tool for visualizing, building and analysing molecular interaction networks. esyN is based on cytoscape.js and its aim is to make it easy...

    Latest version of esyN (Easy Networks) is 2.1 and it was released on 2016-01-17.

    Tags: Bioinformatics Software, Proteomics, Metabolomic Databases, Free Software
  • eMovie by Israel Structural Proteomics Center

    eMovie is a plug-in for PyMOL that makes the creation of molecular movies both easy and intuitive via a breakthrough storyboard interface, similar in nature to what is used in the creation of...

    Tags: Molecular Modelling Software, Data Visualization Software, Bioinformatics Software
  • DNADynamo by BlueTractorSoftware Ltd

    DNADynamo is a commercial DNA sequence analysis software package produced by Blue Tractor Software Ltd that runs on Microsoft Windows, Mac OS X and Linux It is used by molecular biologists to...

    Tags: Bioinformatics Software, Computational Science
  • DECIPHER by Erik Wright

    Decipher, stylized as DECIPHER, is a software toolset that can be used to decipher and manage biological sequences efficiently using the programming language R. Some functions of the program are...

    Latest version of DECIPHER is 2.2.0 and it was released on {{Start date and age|2016}}.

    Tags: Bioinformatics Software, Computational Phylogenetics
  • Cytoscape

    Cytoscape is an open source bioinformatics software platform for visualizing molecular interaction networks and integrating with gene expression profiles and other state data. Additional features...

    Latest version of Cytoscape is 3.5.1 and it was released on 2017-04-26.

    Tags: Bioinformatics Software, Systems Biology, Mathematical And Theoretical Biology, Graph Drawing Software, Crossplatform Software, Java Platform Software
  • CLUSTAL by {{Plainlist| * Des Higgins * Fabian Sievers * David Dineen * Andreas Wilm (all at the Conway Institute, UCD)}}

    Clustal is a series of widely used computer programs used in Bioinformatics for multiple sequence...

    Latest version of CLUSTAL is 1.2.2 and it was released on 2016-07-01.

    Tags: Bioinformatics Software, Computational Phylogenetics
  • CheShift2

    CheShift-2 (pronounced /tʃeʃɪft/) is an application created to compute 13Cα and 13Cβ protein chemical shifts and to validate protein structures. It is based on quantum mechanics computations of 13Cα...

    Latest version of CheShift-2 is 3.0 and it was released on 2013-09-01.

    Tags: Bioinformatics Software
  • Budapest Reference Connectome by Balázs Szalkai, Csaba Kerepesi, Bálint Varga, Vince Grolmusz

    The Budapest Reference Connectome server computes the frequently appearing anatomical brain connections of 418 healthy subjects. It has been prepared from diffusion MRI datasets of the Human...

    Tags: Computational Neuroscience, Neuroscience, Neuroinformatics, Bioinformatics, Bioinformatics Software, Free Bioinformatics Software
  • BLAT by Jim Kent,UCSC

    BLAT (BLAST-like alignment tool) is a pairwise sequence alignment algorithm that was developed by Jim Kent at the University of California Santa Cruz (UCSC) in the early 2000s to assist in the...

    Tags: Bioinformatics Software, Laboratory Software
  • Biskit by Raik Grünberg, Johan Leckner, and others

    Biskit is an open source software package written in Python. The package facilitates research in Structural bioinformatics and molecular modelling. Biskit falls into two parts: * an Object-oriented...

    Tags: Bioinformatics Software, Molecular Modelling, Physics Software, Computational Chemistry Software, Free Science Software, Free Software Programmed In Python, Molecular Dynamics
  • BioPHP

    BioPHP is a collection of open source PHP code, with classes for DNA and protein sequence analysis, alignment, database parsing, and other bioinformatics tools. BioRuby is released under the GNU GPL...

    Tags: Bioinformatics Software, Free Bioinformatics Software
  • BioRuby

    BioRuby is a collection of Open Source Ruby code, comprising classes for computation molecular biology and bioinformatics. It contains classes for DNA and protein sequence analysis, sequence...

    Latest version of BioRuby is 1.5.0 and it was released on 2015-07-01.

    Tags: Bioinformatics Software, Free Bioinformatics Software
  • BioMart

    BioMart is a community-driven project to provide a single point of access to distributed research data. The BioMart project contributes open source software and data services to the international...

    Tags: Bioinformatics Software, Free Software Projects, Biological Databases, Data Warehousing Products
  • BioNumerics by Applied Maths N.V.

    BioNumerics is a suite of bioinformatics software applications developed by the company Applied Maths...

    Tags: Bioinformatics Software
  • Bioinformatic Harvester by Urban Liebel, Björn Kindler

    The Bioinformatic Harvester was a bioinformatic meta search engine created by the European Molecular Biology Laboratory and subsequently hosted and further developed by KIT Karlsruhe Institute of...

    Latest version of Bioinformatic Harvester is 4 and it was released on 2011-05-24.

    Tags: Bioinformatics Software, Biological Databases, Internet Search Engines, Biology Websites
  • Beacon Designer by Premier Biosoft

    Beacon Designer designs highly specific and efficient primers and probes for real time PCR (polymerase chain reaction) assays. It is compatible to work on Windows as well as on Mac. The software...

    Latest version of Beacon Designer is 7.9 and it was released on [wiki=58c032d8e88b253d5577448141ed2384]17 June 2010[/wiki].

    Tags: Bioinformatics Software
  • Archaeopteryx by Christian M. Zmasek

    Archaeopteryx is an interactive computer software program, written in Java, for viewing, editing, and analyzing phylogenetic trees. This type of program can be used for a variety of analyses of...

    Latest version of Archaeopteryx is 0.972+ beta 9M and it was released on 2012.08.08.

    Tags: Bioinformatics Software, Computational Phylogenetics
  • AMPHORA by Martin Wu, Jonathan Eisen et al.

    AMPHORA ("AutoMated Phylogenomic infeRence Application") is an open-source bioinformatics workflow. AMPHORA2 uses 31 bacterial and 104 archaeal phylogenetic marker genes for inferring phylogenetic...

    Latest version of AMPHORA is 2.0 and it was released on 2013.

    Tags: Metagenomics Software, Bioinformatics Software, Free Bioinformatics Software, Computational Phylogenetics, Free Science Software
  • Abalone by Agile Molecule

    Abalone is a general purpose molecular dynamics and molecular graphics program for simulations of bio-molecules in a periodic boundary conditions in explicit (flexible SPC water model) or in...

    Latest version of Abalone is 1.9.0 and it was released on 2016-05-17.

    Tags: Science Software, Molecular Modelling Software, Molecular Dynamics Software, Monte Carlo Software, Bioinformatics Software, Computational Chemistry Software
  • AMAP by Ariel Schwartz (UC Berkeley), Lior Pachter (UC Berkeley)

    AMAP is a multiple sequence alignment program based on a new approach to multiple alignment called sequence annealing. This approach consists of building up the multiple alignment one match at a...

    Tags: Bioinformatics Software
  • AlleleID by PREMIER Biosoft

    AlleleID designs oligos for strain differentiation and taxa specific assays. This aids in bacterial identification, pathogen detection and species identification. The software is designed to run on...

    Latest version of AlleleID is 7.80 and it was released on 29 June 2013.

    Tags: Bioinformatics Software
  • Stemloc by Ian Holmes (UC Berkeley)

    Stemloc is a program for pairwise RNA structural alignment based on probabilistic models of RNA structure known as Pair stochastic context-free grammars. Stemloc implements constrained versions of...

    Tags: Bioinformatics Software
  • SplitsTree by Daniel Huson and David Bryant

    SplitsTree is a popular program for inferring phylogenetic trees or, more generally, phylogenetic networks from various types of data such as a sequence alignment, a distance matrix or a set of...

    Latest version of SplitsTree is 4.14.4 and it was released on 2008.

    Tags: Bioinformatics Software, Computational Phylogenetics, Genetics, Molecular Biology
  • RAPTOR by Bioinformatics Solutions Inc.

    RAPTOR is protein threading software used for protein structure prediction. It has been replaced by RaptorX, which is much more accurate than...

    Latest version of RAPTOR is 4.2 and it was released on {{Start date and age|2008|11}}.

    Tags: Bioinformatics Software, Molecular Modelling Software
  • NoeClone by NoeGen Inc.

    NoeClone is a bioinformatics software which can run in multiple operating systems (Windows, Mac OS, Unix/Linux) with the same...

    Latest version of NoeClone is 2.01 and it was released on 2009.

    Tags: Bioinformatics Software
  • MAFFT by Kazutaka Katoh

    In bioinformatics, MAFFT is a multiple sequence alignment program for amino acid or nucleotide sequences. The software is named after the acronym Multiple Alignment using Fast Fourier Transform...

    Latest version of MAFFT is 7.299 and it was released on 2016-06-28.

    Tags: Bioinformatics Software, Computational Phylogenetics
  • Handel by Ian Holmes (UC Berkeley)

    Handel is a suite of programs for multiple sequence alignment. Since it is based on a model of DNA sequence evolution that explicitly incorporates insertion and deletion events, it effectively...

    Tags: Bioinformatics Software
  • Giant Virus Finder by Csaba Kerepesi

    The Giant Virus Finder is a free bioinformatics software for finding giant viruses in...

    Tags: Metagenomics Software, Bioinformatics Software, Free Bioinformatics Software, Free Science Software
  • GENSCAN by Christopher Burge

    In bioinformatics GENSCAN is a program to identify complete gene structures in genomic DNA. It is a GHMM-based program that can be used to predict the location of genes and their exon-intron...

    Tags: Bioinformatics Software
  • Dendroscope by Daniel Huson et al.

    Dendroscope is an interactive computer software program written in Java for viewing Phylogenetic trees. This program is designed to view trees of all sizes and is very useful for creating figures....

    Latest version of Dendroscope is 3.2.10 and it was released on 2013.

    Tags: Bioinformatics Software, Computational Phylogenetics
  • Apache Taverna by Apache Software Foundation (myGrid for 2.x)

    Apache Taverna is an open source software tool for designing and executing workflows, initially created by the myGrid project under the name Taverna Workbench, now a project under the Apache...

    Latest version of Apache Taverna is 2.5 and it was released on 2014-04-16.

    Tags: Workflow Technology, Bioinformatics Software, School Of Computer Science University Of Manchester, Workflow Software, Apache Software Foundation, Apache Software Foundation Projects, Software Using The Apache License
  • BLAST by Altschul SF,Gish W,Miller W,Myers EW,Lipman DJ,NCBI

    In bioinformatics, BLAST for Basic Local Alignment Search Tool is an algorithm for comparing primary biological sequence information, such as the amino-acid sequences of proteins or the nucleotides...

    Latest version of BLAST is 2.6.0+ and it was released on 2016-12-07.

    Tags: Bioinformatics Algorithms, Computational Phylogenetics, Bioinformatics Software, Laboratory Software, Publicdomain Software
  • HMMER by Sean Eddy, Travis Wheeler, HMMER development team

    HMMER is a free and commonly used software package for sequence analysis written by Sean Eddy. Its general usage is to identify homologous protein or nucleotide sequences, and to perform sequence...

    Latest version of HMMER is 3.0 and it was released on 2010-03-28.

    Tags: Bioinformatics Software, Free Science Software, Free Software Programmed In C, Computational Science
  • MorphoBank by The MorphoBank Project

    MorphoBank is a web application for collaborative evolutionary research, specifically phylogenetic systematics or cladistics, on the phenotype. Historically, scientists conducting research on...

    Tags: Web Applications, Bioinformatics Software
  • OpenMS

    OpenMS is an open-source project for data analysis and processing in protein mass spectrometry and is released under the 3-clause BSD licence. It supports most common operating systems including...

    Latest version of OpenMS is 2.1.0 and it was released on 2016-11-22.

    Tags: Free Science Software, Bioinformatics Software, Mass Spectrometry Software, Proteomics, Software Using The Bsd License
  • UGENE by Unipro

    UGENE is computer software for bioinformatics. It works on desktop computer operating systems such as Windows, macOS, or Linux. It is released as free and open-source software, under a GNU General...

    Latest version of UGENE is 1.27 and it was released on 2017-08-23.

    Tags: Bioinformatics Software, Free Science Software, Free Software Programmed In C, Computational Science
  • NEST by The NEST Initiative

    NEST is a simulation software for spiking neural network models, including large-scale neuronal networks. NEST was initially developed by Markus Diesmann and Marc-Oliver Gewaltig and is now...

    Latest version of NEST (Neural Simulation Tool) is 2.12.0 and it was released on 2017-03-01.

    Tags: Computational Biology, Computational Neuroscience, Simulation Software, Scientific Simulation Software, Science Software, Free Science Software
  • Foldinghome by Pande Laboratory, Sony,Nvidia,ATI, Cauldron Development

    Folding@home (FAH or F@h) is a distributed computing project for disease research that simulates protein folding, computational drug design, and other types of molecular dynamics. The project uses...

    Latest version of Folding@home is 7.4.4 and it was released on 2014-03-19.

    Tags: Computerrelated Introductions In 2000, Bioinformatics, Computational Biology, Computational Chemistry, Crossplatform Software, Data Mining And Machine Learning Software, Distributed Computing Projects, Hidden Markov Models, Mathematical And Theoretical Biology, Molecular Dynamics Software, Molecular Modelling, Molecular Modelling Software, Playstation 3 Software, Proprietary Crossplatform Software, Protein Folds, Protein Structure, Simulation Software, Stanford University, Medical Technology, Medical Research Organizations, Science Software For Linux, Science Software For Macos, Science Software For Windows
  • Freeciv by The Freeciv project

    Freeciv is a single, and multiplayer, turn-based strategy game for workstations and personal computers inspired by the proprietary Sid Meier's Civilization series. It is available for most desktop...

    Latest version of Freeciv is 2.5.9 and it was released on 2017-08-19.

    Tags: 1996 Video Games, 4x Video Games, Amiga Games, Amigaos 4 Games, Aros Software, Articles Containing Video Clips, Browser Games, Cooperative Video Games, Crossplatform Software, Free And Opensource Android Software, Free Software That Uses Sdl, Linux Games, Luascripted Video Games, Maemo Games, Morphos Games, Multiplayer Hotseat Games, Opensource Strategy Video Games, Macos Games, Panhistorical Video Games, Turnbased Strategy Video Games, Video Games With Isometric Graphics, Windows Games
  • Stratagus

    Stratagus is a Free and open-source cross-platform game engine used to build real-time strategy video games. Licensed under the GNU GPL, it is written in C and (mostly) C++ with the configuration...

    Latest version of Stratagus is 2.4.1 and it was released on 2016-11-01.

    Tags: Amigaos 4 Games, Free Game Engines, Free Software Programmed In C, Opensource Strategy Video Games, Linux Games, Luascriptable Game Engines, Luascripted Video Games, Macos Games, Morphos Games, Aros Software, Amiga Games, Opensource Video Games, Realtime Strategy Video Games, Free Software That Uses Sdl, Windows Games, Fangames
  • OpenTTD

    OpenTTD is a business simulation game in which players try to earn money via transporting passengers and freight by road, rail, water and air. It is an open-source remake and expansion of the 1995...

    Tags: Transport Tycoon, Windows Games, Amigaos 4 Games, Linux Games, Morphos Games, Multiplayer Online Games, Cooperative Video Games, Fangames, Free Software Programmed In C, Train Simulation Video Games, Opensource Video Games, Macos Games, Video Games With Isometric Graphics, Video Games With Tilebased Graphics, Transport Simulation Games, Business Simulation Games, Free Software That Uses Sdl, Multiplayer And Singleplayer Video Games, Creative Commonslicensed Video Games
  • MegaZeux by Alexis Janson, Gilead Kutnick, Alistair Strachan and others

    MegaZeux, or MZX, is a game creation system (GCS) inspired by Tim Sweeney/Epic MegaGames' classic shareware game ZZT. MegaZeux was created in late 1994 by Alexis Janson, who formed her own company,...

    Latest version of MegaZeux is 2.84c and it was released on December 24, 2012.

    Tags: Zzt, Amigaos 4 Software, Linux Games, Video Game Engines, Video Game Development Software, Free Software Programmed In C, Free Software Programmed In C
  • Hedgewars by Hedgewars development team

    Hedgewars is a free and open-source turn-based strategy artillery game. Similar to Worms and WarMUX, players control a team of hedgehogs across a deformable landscape, battling other computer- or...

    Latest version of Hedgewars is 0.9.22 and it was released on 2015-11-03.

    Tags: Artillery Video Games, Linux Games, Opensource Strategy Video Games, Opensource Video Games, Video Game Clones, Free Software That Uses Sdl
  • NihongoUp

    NihongoUp was an Adobe AIR desktop Japanese educational game and reviewing tool. The program featured several game modes which allowed the player to improve his kana typing and reading speed, review...

    Latest version of NihongoUp is 1.4.0 and it was released on 2010-09-11.

    Tags: Language Learning Video Games, Adobe Integrated Runtime Platform Software, Japanese Language Learning Resources, Ios Games, Windows Games, Linux Games, Ios Software, Android Software, Spaced Repetition Software, Windows Phone Software, Android Games, Windows Phone Games
  • GNU Go by GNU Go Team

    GNU Go is a free software program by the Free Software Foundation that plays Go. Its source code is quite portable, and can be easily compiled for Linux, as well as other Unix-like systems,...

    Latest version of GNU Go is [https://www.gnu.org/software/gnugo/download.html 3.8] and it was released on 2009-02-19.

    Tags: Go Software, Gnu Project Software, Opensource Video Games, Linux Games, Windows Games, Macos Games, Gp2x Games, Game Boy Advance Games
  • TuxWordSmith by Charles B. Cossé

    TuxWordSmith is a multi-language word game similar to Scrabble in which users play against Tux, the Linux mascott. The game is distributed with over 80 language-language dictionaries courtesy of the...

    Latest version of TuxWordSmith is 0.7.11 and it was released on 18 August 2010.

    Tags: Beos Games, Free Educational Software, Linux Games, Macos Games, Opensource Educational Video Games, Opensource Puzzle Video Games, Opensource Video Games, Windows Games
  • Tux of Math Command by Bill Kendrick,David Bruce,Holger Levsen,Tim Holy, Sam Hart, Brendan Luchen,Jesus Mager

    Tux, of Math Command (TuxMath, for short) is an open source arcade-style video game for learning arithmetic, initially created for...

    Latest version of Tux, of Math Command is 2.0.0 and it was released on 2011-04-14.

    Tags: Beos Games, Free Educational Software, Gnome Kids, Linux Games, Macos Games, Opensource Educational Video Games, Opensource Video Games, Windows Games
  • Tux Typing by community project

    Tux Typing is a free and open source typing tutor created especially for children. It features several different types of game play, at a variety of difficulty levels. It is designed to be fun and...

    Latest version of Tux Typing is 1.8.0 and it was released on 2009-11-10.

    Tags: Software For Children, Typing Software, Linux Games, Opensource Educational Video Games, Free Educational Software, Gnome Kids, Touch Typing Tutors For Linux, Free Software That Uses Sdl, Software That Uses Cairo
  • TuxMathScrabble by Charles B. Cossé

    TuxMathScrabble is a math version of the classic word game Scrabble (Trademark of Hasbro) which challenges kids to construct compound equations and to consider multiple abstract possibilities....

    Latest version of TuxMathScrabble is 0.7.3 and it was released on 18 August 2010.

    Tags: 2001 Software, Beos Games, Free Educational Software, Linux Games, Logic Puzzles, Macos Games, Opensource Educational Video Games, Opensource Puzzle Video Games, Opensource Video Games, Windows Games
  • XBoard by GNU project

    XBoard is a graphical chessboard for the X Window System. It is developed and maintained as free software by the GNU project. WinBoard is a port of XBoard to run natively on Microsoft...

    Latest version of XBoard is 4.9.1 and it was released on 2016-07-31.

    Tags: Free Chess Software, Linux Games, Free Educational Software, Gnu Project Software, Free Software Programmed In C
  • GNU Chess by GNU Project

    GNU Chess is a free software chess engine which plays a full game of chess against a human being or other computer program. The goal of GNU Chess is to serve as a basis for research. It has been...

    Latest version of GNU Chess is 6.2.5 and it was released on 2017-07-24.

    Tags: 1984 Software, Chess Engines, Gnu Project Software, Free Chess Software, Gp2x Games, Linux Games, Windows Games, Dos Games, Free Educational Software
  • Dimension 3

    Dim3, also known as Dimension 3, is a free and open-source 3D game engine created by Brian Barnes. It has been chosen as a staff pick for OS X development software by Apple. and featured as one of...

    Latest version of Dimension 3 is v24 and it was released on July 2, 2014.

    Tags: Free Game Engines, Macos Games, Game Engines For Linux, Free Software That Uses Sdl, Software Using The Mit License
  • ScummVM by ScummVM Team

    Script Creation Utility for Maniac Mansion Virtual Machine (ScummVM) is a set of game engine recreations. Originally designed to play LucasArts adventure games that use the SCUMM system, it also...

    Latest version of ScummVM is 1.9.0 and it was released on 2016-10-17.

    Tags: 2001 Software, Adventure Game Engines, Amiga Software, Amigaos 4 Software, Beos Software, Bsd Software, Crossplatform Software, Dreamcast Emulation Software, Free And Opensource Android Software, Free Software, Free Software Programmed In C, Free Software Projects, Free Virtualization Software, Linux Software, Macos Games, Morphos Software, Os2 Software, Palm Os Software, Pocket Pc Software, Solaris Software, Unix Software, Windows Games
  • Sim RPG Maker 95 by ASCII,Pegasus Japan

    Sim RPG Maker (シミューレーションRPGツクール) is a series of tactical role-playing game software and spinoff of the long-running RPG Maker series, although the name is not a direct translation of the original...

    Latest version of Sim RPG Maker 95 is Sim RPG Maker 95 VALUE! (1.10) and it was released on November 21, 2001.

    Tags: 1998 Video Games, Rpg Maker, Playstation Games, Sega Saturn Games, Tactical Roleplaying Video Games, Video Game Development Software, Windows Games
  • Mavis Beacon Teaches Typing by The Software Toolworks (now part of Brøderbund)

    Mavis Beacon Teaches Typing is an application software program for teaching touch...

    Tags: Advertising Characters, Typing Video Games, Apple Ii Games, Mac Os Games, Amiga Games, Windows Games, Apple Iigs Games, Atari St Games, Typing Software
  • FairyMax by H.G. Muller

    Fairy-Max is a free and open source chess engine which can play orthodox chess as well as chess variants. Among its features is the ability of users to define and use their own custom variant chess...

    Tags: Chess Engines, Chess Variants, Free Chess Software, Windows Games, Windowsonly Free Software
  • ChessV by Gregory Strong

    ChessV (short for Chess Variants) is a free computer program designed to play a large number of chess variants. ChessV is an open-source, universal chess variant program with a graphical...

    Latest version of ChessV is 0.95 and it was released on 2016-11-13.

    Tags: Chess Engines, Chess Variants, Free Chess Software, Windows Games, Windowsonly Free Software
  • DX Studio by Worldweaver Ltd

    DX Studio is a complete integrated development tool for the creation of 3D video games, simulations or real-time interactive applications for either standalone, web based, Microsoft Office or Visual...

    Latest version of DX Studio is v3.2 and it was released on December 1st, 2010.

    Tags: Windows Games, Video Game Development Software, 3d Scenegraph Apis, 3d Graphics Software, Graphics Libraries, Computer Libraries, 2005 Software, Freeware Game Engines